Abstract #3552

Gadoxetate-disodium-enhanced T1-weighted R2* Mapping Improves Visualization of Biliary Anatomy in Liver Donor Candidates

Soudabeh Fazeli Dehkordy¹, Saya Igarashi¹, Carolina P Lamas Constantino^1,2, Jonathan Hooker¹, Cheng William Hong¹, Adrija Mamidipalli¹, Alan Hemming³, and Claude B Sirlin¹

¹Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States, ²Dimagem Diagnóstico por Imagem, Rio de Janeiro, Brazil, ³Department of Surgery, University of California San Diego, San Diego, CA, United States

Gadoxetate-disodium (Gd-EOB-DTPA)-enhanced 3D T1- weighted (T1W) MR cholangiography (MRC) is recognized as an efficient method for evaluation of biliary anatomy, which is critical in the preoperative evaluation of living liver donors. We hypothesize that bile duct visualization could be improved by acquiring Gd-EOB-DTPA-enhanced T1W multi-echo (ME) gradient-echo (GRE) images and generating parametric R2* map cholangiograms. In 10 liver donor candidates, we retrospectively compared biliary duct visualization on T1W-R2* maps vs. 3D T1W cholangiograms obtained 20 minutes after IV administration of gadoxetate disodium. T1W-R2* maps provided comparable visualization of the first-order bile duct branches and better visualization of the second-order branches (p<0.05).

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