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Abstract #3626

A multi-compartment cerebral perfusion phantom to test territory selection using vessel encoded arterial spin labelling

Michael A Chappell1, Bridget Fryer1, Anton Firth1, Robert Wight1, Thomas Kirk1, and Thomas W Okell2

1Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, 2Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

Vessel encoded arterial spin labelling allows the visualisation of perfusion territories in the brain. However, the accuracy of perfusion measurements from VE-ASL and the associated analysis methods is difficult to establish without ground truth. Perfusion phantom devices have been prosed for conventional ASL, but don't currently attempt to model the full cerebral vasculature anatomy of the brain, limiting their value in evaluation of VE-ASL methods. Thus in this work we set out to create a multi-compartment, multi 'artery' perfusion phantom based on normal vascular anatomy.

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