Abstract #3628

Robust 3D pCASL perfusion imaging using a Cartesian Acquisition with Spiral Reordering (CASPR)

Joshua S. Greer^1,2, Xinzeng Wang², Marco C. Pinho^2,3, Ivan Pedrosa^2,3, and Ananth J. Madhuranthakam^2,3

¹Bioengineering, UT Dallas, Richardson, TX, United States, ²Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ³Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Arterial spin labeling can non-invasively measure perfusion, but offers low SNR compared to contrast-enhanced perfusion techniques. A novel 3D TSE with a Cartesian Acquisition with SPiral Reordering (CASPR) was implemented and combined with pCASL in the brain and kidneys. This sampling technique samples the center of k-space early in each echo train, and was shown to provide significantly improved 3D perfusion images compared to 3D linear acquisitions, and more extensive coverage than 2D acquisitions in a similar scan time.

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