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Abstract #3628

Robust 3D pCASL perfusion imaging using a Cartesian Acquisition with Spiral Reordering (CASPR)

Joshua S. Greer1,2, Xinzeng Wang2, Marco C. Pinho2,3, Ivan Pedrosa2,3, and Ananth J. Madhuranthakam2,3

1Bioengineering, UT Dallas, Richardson, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Arterial spin labeling can non-invasively measure perfusion, but offers low SNR compared to contrast-enhanced perfusion techniques. A novel 3D TSE with a Cartesian Acquisition with SPiral Reordering (CASPR) was implemented and combined with pCASL in the brain and kidneys. This sampling technique samples the center of k-space early in each echo train, and was shown to provide significantly improved 3D perfusion images compared to 3D linear acquisitions, and more extensive coverage than 2D acquisitions in a similar scan time.

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