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Abstract #3632

Optimization of Flip Angle Design for Reduced T2 Blurring of 3D Arterial Spin Labeling

Li Zhao1 and David Alsop1

1Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Conventional 3D arterial spin labeling images suffer from pronounced T2 blurring. In this work, new variable flip angle schemes, which can provide a Hann or Fermi window response across the slice direction, or which can be easily corrected to the designed window response and provide optimal SNR, were evaluated. Volunteers’ results show reduced blurring, improved SNR and contrast with the proposed methods.

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