Abstract #3666

Spatiotemporal dynamics of inter-subject magnetic susceptibility variations in the human brain

Balint P Sule¹, Robert Zivadinov^1,2, Jannis Hanspach¹, Michael G Dwyer¹, Jesper Hagemeier¹, Nicola Bertolino¹, Dhaval Shah¹, Niels P Bergsland^1,3, and Ferdinand Schweser^1,2

¹Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, United States, ²MRI Clinical and Translational Research Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, United States, ³MR Research Laboratory, IRCCS, Don Gnocchi Foundation ONLUS, Milan, Italy

Magnetic susceptibility in the deep gray matter varies substantially between subjects of similar age or disease state. This work employs a blind source separation technique to 239 healthy controls to determine, without prior assumptions, the spatial patterns that drive inter-subject variation of magnetic susceptibility in the human brain.

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