Meeting Banner
Abstract #3668

Tikhonov regularization aided quantitative susceptibility mapping of whole brain without background field removal

Hongfu Sun1, Yuhan Ma1,2, M. Ethan MacDonald1, and G. Bruce Pike1,2

1Radiology, University of Calgary, Calgary, AB, Canada, 2Biomedical Engineering, McGill University, Montreal, QC, Canada

An advanced dipole field inversion method for whole brain quantitative susceptibility mapping (QSM) without a traditional background field removal step, is proposed. To aid this ill-posed inversion process and obtain successful QSM, a Tikhonov regularization of the local susceptibility distribution is included. It is shown that the proposed method (Tikhonov-QSM) can substantially suppress reconstruction artefacts. More importantly, Tikhonov-QSM does not require edge erosion like in other QSM methods involving background field removal steps, preserving the cerebral cortex of the final images.

This abstract and the presentation materials are available to members only; a login is required.

Join Here