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Abstract #3672

What causes streaking artifacts in QSM and how to efficiently suppress them?

Liangdong Zhou1, Jae Kyu Choi2, Youngwook Kee3, Yi Wang3,4, and Jin Keun Seo1

1Department of Computational Science and Engineering, Yonsei University, Seoul, Korea, Republic of, 2Institute of Natural Sciences, Shanghai Jiao Tong University, Shanghai, People's Republic of China, 3Department of Radiology, Weill Cornell Medical College, New York, NY, United States, 4Department of Biomedical Engineering, Cornell University, New York, NY, United States

We provide a mathematical understanding for artifacts in QSM, particularly streaking artifacts. 1) The local field data can be decomposed into a dipole-compatible part and a dipole-incompatible part. 2) In spatially continuous space, the streaking-free susceptibility solution is obtained from the dipole-compatible field data only, and the dipole-incompatible data leads to artifacts defined by a wave propagator with z as time, specifically, streaking artifacts from granular noise and shadow artifacts from white matter noise error. Although it is not known how to filter out such dipole-incompatible data, its artifacts can be suppressed in regularization-based Bayesian methods such as MEDI, which can efficiently penalize streaking artifacts. k-space-truncation-based methods that generate additional dipole-incompatible data near the zero cone amplify streaking artifacts.

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