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Abstract #3681

Evaluation of Accuracy of MR phase and R2* for susceptibility quantification

Yongquan Ye1, Li Yang2, Mengsu Zeng2, Shengxiang Rao2, Ying Ding2, Jinguang Zong3, and Xixi Wen3

1United Imaging of Healthcare America, Houston, TX, United States, 2Department of Radiology, Shanghai Institute of Medical Imaging, Zhongshan Hospital, Fundan University, Shanghai, People's Republic of China, 3Shanghai United Imaging of Healthcare, Shanghai, People's Republic of China

Computer simulation was performed to evaluate the relationship between a voxel's bulk susceptibility and its R2* or phase behavior. A virtual voxel with multi-dipole model was created, and the effects of dipole properties on the accuracy and consistency of R2* and phase on reflecting the voxel’s bulk susceptibility was investigated. Linearity is only observed at low bulk susceptibility regime, and phase is much more robust against various susceptibility dipole properties than R2*.

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