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Abstract #3697

Analysis of the feasibility in using the SPICE technique for hyperpolarized 13C

Jae Eun Song1, Hansol Lee1, Eunhae Joe1, Jaewook Shin1, and Dong-Hyun Kim1

1Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of

In this study, using high spatial and/or spectral resolution CSI technique in 1H, the SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation), we investigated the feasibility of using SPICE in hyperpolarized 13C through numerical simulations for applications targeted for Kp estimation and high resolution studies. The error of the fitted Kp were within ±20% of the true value and the high spatial resolution rat brain image was reconstructed. It is seen that this method can be transferred to a hyperpolarized 13C situation where due to the T1 decay and metabolite exchange the temporal basis can change dynamically.

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