Abstract #3697

Analysis of the feasibility in using the SPICE technique for hyperpolarized 13C

Jae Eun Song¹, Hansol Lee¹, Eunhae Joe¹, Jaewook Shin¹, and Dong-Hyun Kim¹

¹Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of

In this study, using high spatial and/or spectral resolution CSI technique in 1H, the SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation), we investigated the feasibility of using SPICE in hyperpolarized ¹³C through numerical simulations for applications targeted for K_p estimation and high resolution studies. The error of the fitted K_p were within ±20% of the true value and the high spatial resolution rat brain image was reconstructed. It is seen that this method can be transferred to a hyperpolarized ¹³C situation where due to the T1 decay and metabolite exchange the temporal basis can change dynamically.

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