Prospective gating and automatic reacquisition of data corrupted by respiration motion were implemented in variable flip angle (VFA) and actual flip angle imaging (AFI) scans to enable cardio-respiratory synchronised T1 mapping of the whole mouse. T1 calculation for each mouse took approximately 6 s using a robust and efficient nonlinear least squares process. 16 cardio-respiratory gated VFA scans and a respiration gated AFI scan were acquired in less than 14 minutes. T1 was calculated in the whole mouse with a voxel size of 0.075 mm3 and with a standard deviation less than 6.2% within ROIs from multiple organs.
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