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Abstract #3792

Measurement of R2 dispersion profiles using Fast Field Cycling MRI

Nicolas Chanet1, Geneviève Guillot1, and Ludovic de Rochefort2

1IR4M (Imagerie par Résonance Magnétique Médicale et Multi-modalités), Univ. Paris-Sud, CNRS, UMR8081, Université Paris-Saclay, Orsay, France, 2Aix Marseille Univ., CNRS, CRMBM UMR 7339, Marseille, France

Fast Field Cycling (FFC) MRI enables rapid and precise relaxometry measurements as a function of magnetic field B0. Up to now, it was possible to measure longitudinal R1-NMRD profiles and to generate innovative R1-dispersive contrasts. However, the ability to measure transverse R2-NMRD profiles has still to be investigated. Here, a spin-echo based FFC sequence is developed to measure R2-dispersion, and is applied to ferritin and Gd-DOTA in the range 1.15 to 1.85 T. It is shown that measurements of R2 dispersion could be obtained accurately with the FFC-MRI technology.

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