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Abstract #3888

Intensity inhomogeneity correction of whole body fat-water images using fat and water fraction information on a 3T PET/MR scanner

Therese Sjöholm1, Simon Ekström1, Filip Malmberg1,2, Robin Strand1,2, Magnus Johansson1, Lars Lind3, Mathias Engström4, Håkan Ahlström1,5, and Joel Kullberg1,5

1Radiology, Uppsala University, Uppsala, Sweden, 2Centre for Image Analysis, Uppsala University, Uppsala, Sweden, 3Medical Sciences, Uppsala University, Uppsala, Sweden, 4Applied Science Laboratory, GE Healthcare, Uppsala, Sweden, 5Antaros Medical, Mölndal, Sweden

We describe and evaluate a method for intensity non-uniformity correction of whole-body fat-water MR data acquired with both surface and body coils on a 3T PET/MRI system. The proposed method consists of two steps. Abrupt station intensity changes are first supressed, followed by correction of smooth intensity changes using fat and water fraction information. Visual and quantitative evaluations of 42 corrected fat-water datasets show that the method gives improved adipose and lean tissue uniformity for both surface and body coil acquisitions. This renders the data suitable for continued analysis in a whole-body imaging framework.

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