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Abstract #3908

Robust B1 Mapping with Phase-sensitive Orthogonal Excitation RF Pulses

Jie Wen1, Alexander Sukstansky1, and Dmitriy Yablonskiy1

1Radiology, Washington University in St. Louis, St. Louis, MO, United States

Accurate B1 measurement is important in many MR related applications. In this study, we proposed and optimized a phase-sensitive approach for B1 mapping that relies on a multi-gradient-echo sequence with two successive orthogonal RF pulses used for signal excitation. We also proposed optimized methods for combining multi-channel data, allowing for optimal parameters’ estimation. The method was validated on phantoms and tested on human participants. By applying this method on SMART (Simultaneous Multi-Angular Relaxometry of Tissue) MRI, we reaffirmed the importance of the B1 correction for quantifying biological tissues relaxation and magnetization transfer parameters.

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