Abstract #3946

A novel and robust reconstruction method for free-breathing cine DENSE by minimizing k-space entropy

Xiaoying Cai¹, Kenneth C Bilchick², and Frederick H Epstein^1,3

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Medicine, University of Virginia, Charlottesville, VA, United States, ³Radiology, University of Virginia

A reliable free-breathing (FB) cine DENSE method would benefit myocardial strain imaging in many patients. An echo due to T1 relaxation is an important source of artifacts, particularly for free-breathing acquisitions. We propose to optimize suppression of these echoes by minimizing k-space entropy. The method was tested in 10 subjects (6 healthy volunteers and 4 heart failure patients) and compared to a conventional diaphragm navigator method (dNAV). Image reconstruction by minimizing k-space entropy provided better image quality than the conventional dNAV method.

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