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Abstract #3963

Partial Fourier techniques in single-shot cross-term spatiotemporal encoding (xSPEN) MRI

Zhiyong Zhang1 and Lucio Frydman1

1Weizmann Institute of Science, Rehovot, Israel

xSPEN is a new single-shot imaging approach with exceptional resilience to field heterogeneities: its images do not suffer from miss-registrations, require a priori information nor use post-acquisition corrections, to deliver faithfully the spins’ spatial distribution. xSPEN, however, suffers from SNR penalties due to its non-Fourier nature and its considerable diffusion losses –especially when desiring high resolution. This study introduces partial Fourier transform approaches that acting along either the readout or the spatiotemporally-encoded dimensions, reduce both of these penalties. The principles of these partial FT methods are given, and applications in materials, preclinical and human single-shot xSPEN imaging are presented.

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