Two-point Dixon methods enable robust fat suppression particularly in body and abdominal applications where large field of view imaging is required. However, a limitation of this approach is the decreased efficiency and longer TR’s necessary to acquire multiple echoes. Furthermore, due to system performance constraints, flexible choice of image parameters necessary to obtain near in and out-of-phase echo times limits valid combinations of field of view, matrix size, and encoding bandwidth. In this study, we describe a novel, generalized framework to optimize a ramp-sampled readout, which allows reduced scan time, flexible parameter selection, and improved quantitative fat and water separation.
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