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Abstract #3969

Evaluation of phase-cycled bSSFP for qMT mapping in the brain in off-resonance conditions

Nicholas G Dowell1, Nathan Evans2, and Mara Cercignani1

1CISC, BSMS, Brighton, United Kingdom, 2Physics, University of Sussex, Brighton, United Kingdom

The balanced steady-state free precession acquisition approach is well-suited to quantitative magnetization transfer studies, owing to intrinsic MT weighting, rapid acquisition times and good SNR. However, the presence of off-resonance banding artefacts have limited its use, especially at B0>1.5T. This work is the first to evaluate a phase-cycled approach to bSSFP that can remove banding artefacts by taking maximum intensity projection MIP or taking a weighted mean as part of the qMT analysis. We conclude that neither MIP and weighted mean alone are capable of fully removing banding artefacts from qMT maps.

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