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Abstract #3998

High-Resolution DWI Using Multishot Variable Density Spiral with SPIRiT-Based Reconstruction

Zijing Dong1, Xiaodong Ma1, Fuyixue Wang1,2, Chun Yuan1,3, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, 2Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 3Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

Multishot variable density spiral is an efficient sequence for diffusion imaging with the oversampled k-space center serving as a navigator. However, the shot-to-shot phase variation of multishot acquisition due to motion must be corrected. To improve the reconstruction accuracy, we propose a novel reconstruction framework using SPIRiT-based reconstruction, integrating the information of phase variation and coil sensitivity in order to correct for the ghosting artifacts of multi-shot DWI. Both simulation and in-vivo experiment validated the superior performance of the proposed method to reconstruct more accurate images than CG-SENSE for VDS DWI.

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