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Abstract #4103

Music training enhances functional connectivity in preterm newborns

Serafeim Loukas1,2, Lara Lordier1,3, Frédéric Grouiller4, Didier Grandjean3, François Lazeyras5, Dimitri Van de Ville2,5, and Petra S. Hüppi1

1Division of Development and Growth, Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland, 2Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Neuroscience of Emotion and Affective Dynamics Lab, Department of psychology, University of Geneva, Geneva, Switzerland, 4Swiss center for affective neurosciences, University of Geneva, Geneva, Switzerland, 5Department of Radiology and Medical Informatics, University of Geneva, Geneva, Switzerland

In this study we examined the impact of the environmental enrichment of preterm newborns with music on auditory cortex functional connectivity. A group of preterm infants listened to music from 33 weeks gestational age until term equivalent age. Two control groups were used: preterm and full-term infants without music. Auditory cortex functional connectivity with cerebral regions known to be implicated in tempo and familiarity processing were identified for preterm newborns that had music training during their stay in the NICU using Psychophysiological Interaction (PPI) analyses. Our results suggest that music training during hospitalization can modify functional connectivity in the newborn brain.

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