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Abstract #4177

Diffusion kurtosis imaging: a novel tool to evaluate survival of glioma patients

Rifeng Jiang1, Wenzhen Zhu2, Lingyun Zhao2, Qing Duan1, Yunjing Xue1, and Jingjing Jiang2

1Fujian Medical University Union Hospital, Fuzhou, People's Republic of China, 2Tongji Hospital, HUST, Wuhan, People's Republic of China

DKI is a promising tool to predict the survival of glioma patients. MK, MD and ADC were significantly correlated with overall survival (OS) of patients with astrocytic tumor. By univariate Kaplan-Meier survival analyses, OS of the patients was related to tumor grade, Ki-67 LI, resection status, enhancement degree, edge, edema degree, lesion number, MK, MD and ADC (log rank p < 0.05 for all). Multivariate Cox regression analysis indicated that MK is an independent predictor of OS in these patients, and it is a risk factor (P = 0.006, HR=2.142 and 95%CI=1.247-3.679 for MK increasing every 0.1). These results are helpful to clinic.

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