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Abstract #4192

Partial Volume Effects in Arterial Spin Labelling: Something to Live With or Correct For?

Michael A Chappell1, Iris Asllani2, Xavier Golay3, Matthias G√ľnther4,5,6, Juan A Hern√°ndez-Tamames7, and Matthias J.P van Osch8

1Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, 2Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, NY, United States, 3Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom, 4Fraunhofer MEVIS, Bremen, Germany, 5University Bremen, Bremen, Germany, 6mediri GmbH, Heidelberg, Germany, 7Radiologie & Nucleaire Geneeskunde, Erasmus MC, Rotterdam, Netherlands, 8C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands

Partial Volume Effects have a profound influence on the perfusion images generated using Arterial Spin Labelling. We are only starting to appreciate how this influences our interpretation of the images and what we can discover when using perfusion imaging in studies. This e-poster seeks to outline the key issues, underlying theory about what effects PVE might have, methods to correct for them, and when correction may or may not be a good idea.

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