Abstract #4192

Partial Volume Effects in Arterial Spin Labelling: Something to Live With or Correct For?

Michael A Chappell¹, Iris Asllani², Xavier Golay³, Matthias Günther^4,5,6, Juan A Hernández-Tamames⁷, and Matthias J.P van Osch⁸

¹Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, ²Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, NY, United States, ³Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom, ⁴Fraunhofer MEVIS, Bremen, Germany, ⁵University Bremen, Bremen, Germany, ⁶mediri GmbH, Heidelberg, Germany, ⁷Radiologie & Nucleaire Geneeskunde, Erasmus MC, Rotterdam, Netherlands, ⁸C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands

Partial Volume Effects have a profound influence on the perfusion images generated using Arterial Spin Labelling. We are only starting to appreciate how this influences our interpretation of the images and what we can discover when using perfusion imaging in studies. This e-poster seeks to outline the key issues, underlying theory about what effects PVE might have, methods to correct for them, and when correction may or may not be a good idea.

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