We herein report the 4 cases of brain abscess secondary to odontogenic infection due to an untreated tooth decay. In all cases, there were no abnormalities on physical and intraoral examinations, nor overt trismus or facial swelling. Dental CT showed a periapical radiolucency around the root tips of a decayed tooth, which revealed periodontal abscess. After the multidisciplinary therapy including antibiotics, abscess drainage, and dental treatments, all the patients recovered and discharged.
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