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Abstract #4207

Image Quality Comparison of High Resolution PC-MRA (4D-Flow) with Time of Flight in Healthy Volunteers

Warren Chang1, Michael Loecher1, Daniel B Ennis1, Aichi Chien1, and J. Pablo Villablanca1

1Department of Radiological Sciences, University of California, Los Angeles, CA, United States

In this study, image quality of high resolution PC-MRA (4D Flow) and 3D-TOF was compared. Ten healthy volunteers were scanned with high resolution 4D-Flow and 3D-TOF angiograms at 0.5 mm isotropic spatial resolution in clinically-useful scan times of 7 and 12 minutes. There was no significant difference in image quality between 4D Flow and 3D-TOF in both source images and MIPs. 4D Flow acquisitions were velocity encoded, allowing hemodynamic evaluation of intracranial structures. This study demonstrated that phase-contrast techniques such as 4D-Flow have comparable image quality to 3D-TOF while obtaining velocity measurements, showing promise as a viable alternative to 3D-TOF.

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