The objective of this study, was to differentiate low from high grade glioma using texture analysis of quantitative ADC maps, and further aimed at revealing the microscopic changes of glioma in the evolution of low grade to high grade.Conclusion that texture analysis of ADC signal value based on entire tumor could provide more information in differentiation of low and high grade glioma. Through logistic regression analysis we obtain skewness, entropy,long run emphasis are the independent influence factors, and joint application of them showed superior diagnostic value.
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