Abstract #4369

The use of DCE MRI in predicting early chemo-radiotherapy treatment response for Larynx and hypopharynx carcinoma

Wei Guo¹, Dehong Luo¹, Xinyi Chen², Bing Wu³, Meng Lin¹, Lin Li¹, Yanfeng Zhao¹, Xinming Zhao¹, and Chunwu Zhou¹

¹Radiology, Peking Union Medical College, Cancer Institute & Hospital, Chinese Academy of Medical Sciences, BeiJing, People's Republic of China, ²Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, HangZhou, People's Republic of China, ³GE MR Research China

In this work, we evaluated the utility of pretreatment semi-quantitative dynamic contrast-enhanced magnetic resonance imaging (MRI) in predicting early response to CRT (chemo-radiotherapy) in patients with larynx and hypopharynx carcinoma from primary tumors. To our knowledge, few studies correlate DCE-MRI semi-quantitative parameters on larynx and hypopharynx carcinoma. These quantitative methods do not require high computational power and were very suitable for clinical application.

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