Abstract #4398

Optimization of b-values in iShim diffusion-weighted MR imaging of the thyroid gland: to improve the visualization of malignant thyroid nodules and the accuracy in differentiating malignant from benign thyroid nodules

Qingjun Wang¹, Qinglei Shi², Tianyi Qian³, Alto Stemmer⁴, and Yong Guo¹

¹Department of Radiology, Chinese Navy General Hospital, Beijing, People's Republic of China, ²Scientific Marketing, Siemens Healthcare, People's Republic of China, ³MR Collaobration, HC NEA MR COL, Siemens Healthcare, People's Republic of China, ⁴MR Application Predevelopment, Siemens Healthcare GmbH

To investigate the optimal b-values of diffusion-weighted imaging (DWI), a prototype sequence with integrated slice-specific shimming (iShim) was applied for visualizing thyroid malignant nodules and making accurate differentiation between benign and malignant nodules. DWI images were acquired with five b-values including 0, 800, 1000, 2000 and 3000 sec/mm². The results show that the iShim-DWI with b-value of 800 s/mm² can present the clearest delineation of malignant thyroid nodules and that the images with b-value of 3000 s/mm² had the best performances in differentiating malignant from benign thyroid nodules.

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