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Abstract #4405

Unified Proton and Fluorine Imaging of Small and Low Spin Density Samples at a Human Whole-Body 7 T MRI

Christian Bruns1, Tim Herrmann1, Markus Plaumann1, Chang-Hyun Oh2, Chulhyun Lee 3, Suchit Kumar4, and Johannes Bernarding1

1Department for Biometrics und Medical Informatics, Otto-von-Guericke University, Magdeburg, Germany, 2Department of Electronics and Information Engineering, and Korea Artificial Organ Center, Korea University, Seoul, Korea, Republic of, 3Bioimaging Research Team, Korea Basic Science Institute, Ochang, Korea, Republic of, 4Department of Biomicrosystem Technology and Korea Artificial Organ Center, Korea University, Seoul, Korea, Republic of

In order to provide a system, which allows imaging of 19F MR contrast agents, an in-house-built 19F/1H transmit/receive system for 7 T was successfully tested in a human whole-body 7 T MRI system. This system enables the measurement of concentrations of 1.85 mM. For this approach we used a 19F tuned coil which provided still enough signal gain at the proton frequency to allow 1H imaging for comparison. This showed the possibility of using 19F as contrast agents with a quite simple coil design in comparison to other dual tuned approaches.

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