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Abstract #4409

Characteristics of fat in orbits of patients with early-stage hyperthyroidism

Huajie Jiao1, Rongrong Zhu2, Kaining Shi3, Yong Yang4, and Weiheng He4

1Ningxia people's hospital, yinchuan, People's Republic of China, 2Medical Imaging center, Ningxia people's hospital, People's Republic of China, 3Philips HealthCare, Beijing,china, People's Republic of China, 4People's Republic of China

Summary: Exophthalmos caused by muscle thickening and fat increasing in orbit is the typical symptom in hyperthyroidism, which impairs multiple systems as the auto-immune disease. From this study, we found the increase of percentage of fat and T2* value using the fat quantification analysis package, which indicate the accumulation and differentiation of fat-oriented cells, inflammation cells infiltration and collagen mucous change. Therefore, the characteristics of fat change in orbit can be evaluated by the transverse six-echo proton density fat fraction (PDFF) sequence (mDIXON-quant) technique in early-stage hyperthyroidism without significant manifestation of eyes.

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