Abstract #4416

34 µm Isotropic Resolution MRI of Rat Brain using 55K cryo-probe

Kurt H Bockhorst¹, Jarek Wosik^2,3, and Ponnada A Narayana¹

¹Diagnostic and Interventional Imaging, University of Texas, Health Science Center-Houston Medical School, Houston, TX, ²Electrical and Computer Engineering, University of Houston, Houston, TX, United States, ³Texas Center for Superconductivity

We report on the performance and development of a 300-MHz (7 T) cryogenic receive- only surface coil for MRI of rat brain. Practical performance limits of the cryo-coil were tested such as SNR gains at 55 K for a 19 mm in diameter Cu coil and its frequency stability over long (up to a few days) scans. 3D-RARE isotropic images of ex-vivo rat brain up to 512 slices with outstanding isotropic resolution of 34 μm were acquired showing structural details not seen with conventional small animals coils. In addition, a comparison of such images with matching histological plates is discussed.

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