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Abstract #4425

Improved local sensitivity in magnetic resonance spectroscopy at 3 T using a new flexible and compact metasurface

Rita Schmidt1, Assaf Tal2, and Andrew Webb1

1Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Chemical Physics, Weizmann Institute of Science, Rehovot, Israel

Magnetic resonance spectroscopy is a powerful technique for in-vivo measurement of metabolites, however its sensitivity is limited due to very low concentration of the metabolites. This is especially valid for studies of neurotransmitters such as glutamate and GABA. In this study, a new hybrid metasurface comprising of conducting strips and agar-gel was designed to improve MR sensitivity at 3T. The metasurface forms a compact and flexible pad which is placed in the vicinity of the region of interest. The measurements focused on MRS acquisitions including PRESS and MEGA-PRESS, showing an improvement in SNR of a factor of 1.75, 2 cm from the pad.

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