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Abstract #4456

USPIOs for metastatic lymph node detection in prostate cancer: back on the block

Tom W Scheenen1, Ansje Fortuin1, Janine van der Linden2, Ilia Panfilov1, Bas Israel1, Roger Br├╝ggeman2, and Jelle Barentsz1

1Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, Netherlands, 2Pharmacology, Radboud university medical center, Nijmegen, Netherlands

The presence of nodal metastases in patients with prostate cancer is a key factor determining prognosis and treatment. With the reintroduction of ferumoxtran-10-enhanced MRI in local clinical practice, small metastases in lymph nodes down to 2 mm in size can be detected non-invasively, avoiding diagnostic surgical lymph node dissections and guiding personalized treatment of patients with prostate cancer at intermediate and high risk for metastatic spread.

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