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Abstract #4554

T1 mapping from variable flip angle SPGR and IR-SPGR data using DESPOT1-HIFI

Mohammad Kayvanrad1,2

1Amirkabir University of Technology, Tehran, Iran, 2Robarts Research Institute, London, Canada

This work aims at improving the calculation of T1 maps at high magnetic fields from a set of VFA SPGR and IR-SPGR images for direct correction of B1 inhomogeneities using DESPOT1-HIFI. In the present work we (i) call attention to an erroneous assumption regarding the IR-SPGR signal intensity equation in the original DESPOT1-HIFI method and derive an alternative equation, and (ii) propose a reduced-dimensions least-squares fitting method, which turns the complex multi-parameter fitting into a simple one-dimensional search.

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