Abstract #4578

Ischemic brain lesions and cognition in patients with aneurysmal subarachnoid hemorrhage.

Mariska E Hendriks¹, Irene MC Huenges-Wajer², Theo D Witkamp³, Jeroen Hendrikse⁴, Gabriel JE Rinkel⁴, Johanne MA Visser-Meily⁴, Mervyn DI Vergouwen⁴, and Jill B De Vis⁵

¹Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ²Rehabilitation, University Medical Center Utrecht, ³University Medical Center Utrecht, Netherlands, ⁴University Medical Center Utrecht, ⁵Radiology, University Medical Center Utrecht, Washington, DC, United States

A significant amount of patients with aneurysmal subarachnoid hemorrhage suffer from cognitive impairment. The exact origin of this cognitive impairment is unclear. Lesions developing in relation to the event have been hypothesized as the mechanism of action. However, literature on this topic is inconclusive. We aimed to scrutinize this by analyzing our cohort of patients. Lesions were found in 60% of patients, no relation was found with cognitive outcome, This could be due to selection bias as most of the included patients had a good or mild impaired clinical status at admission and demonstrated ‘no cognitive impairment’ at follow-up.

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