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Abstract #4663

Dynamic Contrast-Enhanced MRI Predicts Short-Term Control of Nasopharyngeal Carcinoma within 5 fractions Intensity-Modulated Radiotherapy

Dechun Zheng1, Yunbin Chen1, Meng Liu1, Hao Lin1, Xiaoxiao Zhang1, Qiuyuan Yue1, Wang Ren1, Weibo Chen2, and Queenie Chan3

1Radiology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou, People's Republic of China, 2MR Clinical Science, Philips Healthcare, 3Philips Healthcare

Many quantitative DCE-MRI based studies suggested it had utility in early monitoring radiotherapy and chemotherapy sensitivity in anti-tumor treatment. However, there are a few studies investigated whether it could been used for predicting IMRT effect and to what extend of its performance would be. This study enrolled 87 patients who received DCE-MRI one week before NAC and one week after IMRT treatment and suggested there were collaboration the kinetic parameters of quantitative DCE-MRI in early assessing IMRT treatments in NPC.

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