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Abstract #4666

Positional variation of parotid glands in the treatment position of head and neck radiotherapy with immobilization: a pilot study on healthy volunteers using high spatial resolution 3D MRI at 1.5T

Jing Yuan1, Yihang Zhou1, Oilei Wong1, Winky Wing Ki Fong2, George Chiu2, Kin Yin Cheung1, and Siu Ki Yu1

1Medical physics and research department, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong, 2Department of Radiotherapy, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong

Investigation of positional and geometric variations of organ-at-risk (OAR) in head-and-neck (HN) radiotherapy (RT) is greatly limited by the poor soft tissue contrast of X-ray-based imaging. We investigated the positional variation of parotid glands (PG) in the immobilized HN-RT treatment position on healthy volunteers using high-spatial-resolution 3D-MRI at 1.5T. The results showed that PGs generally had sub-millimeter and sub-degree group mean error, systematic error and random error under immobilization. Although PGs generally showed insignificant positional variations from global HN, individual left and right PG might move independently and resulted in insignificant positional correlations with each other and global HN.

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