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Abstract #4688

IIT Human Brain Atlas: Enhancement of T1-weighted Template, Tissue Probability Maps and Gray Matter Atlas

Xiaoxiao Qi1, Shengwei Zhang1, and Konstantinos Arfanakis1

1Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States

The IIT Human Brain Atlas contains anatomical, DTI, HARDI templates, probabilistic gray matter (GM) labels, probabilistic connectivity-based white matter labels, and major fiber-bundles of the young adult brain. During development of the atlas, spatial normalization was accomplished based on diffusion data. Consequently, matching of the anatomical information of T1-weighted images was not maximized, blurring the T1-weighted template and tissue probability maps, increasing the noise of the T1-weighted template, and lowering confidence of GM labeling and GM label precision. The present work enhanced the quality of the T1-weighted template, tissue probability maps, and GM labels of the IIT Human Brain Atlas.

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