Meeting Banner
Abstract #4693

Inter-individual variability in rapid eye movement sleep is associated with brain white matter structure

Shuqin Zhou1, Qihong Zou2, Jing Xu2, Jiahui Deng3, Zihui Su2, Tianyi Qian4, Thomas Beck5, Changwei Wu6, Hongqiang Sun3, and Jia-Hong Gao2

1Department of Biomedical Engineering, Peking University, Beijing, People's Republic of China, 2Center for MRI Research and Beijing City Key Lab for Medical Physics and Engineering, Peking University, Beijing, People's Republic of China, 3Sixth Hospital, Peking University, Beijing, People's Republic of China, 4MR Collaborations NE Asia, Siemens Healthcare, Beijing, People's Republic of China, 5Application Development, Siemens Healthcare, Erlangen, Germany, 6Graduate Institute of Humanities in Medicine, Taipei Medical University, Taipei, Taiwan

Previous animal studies indicated that sleep is important for cell membrane and myelin maintenance in the brain. Research further suggests that variability in sleep structure may be associated with brain white matter microstructure. In this study, we investigate the relationship between sleep structure parameters evaluated with polysomnography and brain white matter characteristics, as measured by MR diffusion tensor imaging. We find that inter-subject variability of regional white matter characteristics may explain the differences in sleep structure across participants.

This abstract and the presentation materials are available to members only; a login is required.

Join Here