Meeting Banner
Abstract #4783

Single Slice vs. Volumetric Analysis of Multiparametric Prostate MRI Metrics

Edward William Johnston1, Clare Allen2, Michela Antonelli3, Nikolaos Dikaios1, Sebastien Ourselin3, and Shonit Punwani1

1Centre for Medical Imaging, University College London, London, United Kingdom, 2Radiology, University College London Hospitals, London, United Kingdom, 3Centre for Medical Image Computing, University College London, London, United Kingdom

Despite consensus guidelines advising volumetric analysis of tumours over single slice region-of-interest analysis, there is little data in the literature to support this recommendation. In this study we compare the reproducibility between each of these two methods in 20 patients with prostate cancer and also determine the intraobserver repeatability of each method. We show high levels of agreement and intraobserver repeatability in both of these methods. This study suggests that region-of-interest analysis is a perfectly acceptable analytical method and may have higher intraoberver repeatability than volumetric analysis, and could expedite the analysis of multiparametric prostate MRI datasets in clinical trials.

This abstract and the presentation materials are available to members only; a login is required.

Join Here