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Abstract #4828

Amplitude-probability sorting for single-pass, retrospective 4D-MRI using 2D bSSFP MRI with interleaved cylindrical navigators

Erik Tryggestad1, Ersin Bayram2, Yanle Hu3, Daniel Litwiller4, Dan Rettmann2, Matthew Walb1, Darin White5, and Kiaran McGee5

1Radiation Oncology, Mayo Clinic, Rochester, MN, United States, 2GE Healthcare, Waukesha, WI, United States, 3Radiation Oncology, Mayo Clinic, Phoenix, AZ, United States, 4GE Healthcare, New York, NY, United States, 5Radiology, Mayo Clinic, Rochester, MN, United States

With MRI being increasingly incorporated in the radiotherapy workflow, the multidisciplinary community has a strong interest in developing “4D-MRI” techniques for both offline (tumor motion characterization for treatment planning) and online (tumor motion tracking) applications. In a cohort of 10 volunteers, the present study applied 2D (coronal) bSSFP with interleaved cylindrical navigators monitoring the liver dome to retrospectively derive 4D-MRI comparing two sorting methods, namely phase and amplitude-probability. Amplitude-probability binning was shown, both qualitatively and quantitatively, to reduce “volume inconsistencies” caused by variable breathing.

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