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Abstract #4845

A novel portable perfusion phantom for quantitative DCE-MRI of the abdomen

Harrison Kim1, Mina Mousa, Patrick Schexnailder, Mark Bolding, Robert Hergenrother, Vinoy Thomas, and Desiree Morgan

1University of Alabama at Birmingham, Birmingham, AL, United States

We developed a perfusion phantom that reduced variability in quantifying perfusion parameters of human abdominal tissues across different MR units. The phantom is compact enough to be imaged with the human subject and large enough to not suffer from partial volume effect, thus MR system calibration can be implemented simultaneously with patient imaging. Since it is composed of inexpensive materials, the phantom can be constructed as a disposable device. It is simple to use, so clinical MRI technologists should be able to operate it routinely. This phantom has the potential to facilitate multi-institutional clinical trials employing quantitative DCE-MRI to evaluate various abdominal malignancies.

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