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Abstract #4856

Comparison of Renal Blood Flow Measurements obtained using ASL-MRI and CT Perfusion

Vanessa L. Landes1, Christopher M. Ferguson2, Hung P. Do1, John R. Woollard2, James D. Krier2, Lilach O. Lerman2, and Krishna S. Nayak1

1University of Southern California, Los Angeles, CA, United States, 2Mayo Clinic, Rochester, MN, United States

Computed tomography perfusion (CTP) is a validated method for assessment of single-kidney renal blood flow (RBF), but is limited by the use of exogenous contrast (i.e. iodine) injection and ionizing radiation. Arterial Spin Labeling (ASL)-MRI is an emerging technique that quantitatively measures RBF without any contrast agents or ionizing radiation. We compared renal perfusion (RBF/gram tissue) obtained using CTP and ASL-MRI in the left and right cortex and medulla of the same pigs (n=6), and observed a linear fit of ASL-MRI = 0.24*CTP+0.42 ml/ml/min with correlation r2=0.71.

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