Abstract #4856

Comparison of Renal Blood Flow Measurements obtained using ASL-MRI and CT Perfusion

Vanessa L. Landes¹, Christopher M. Ferguson², Hung P. Do¹, John R. Woollard², James D. Krier², Lilach O. Lerman², and Krishna S. Nayak¹

¹University of Southern California, Los Angeles, CA, United States, ²Mayo Clinic, Rochester, MN, United States

Computed tomography perfusion (CTP) is a validated method for assessment of single-kidney renal blood flow (RBF), but is limited by the use of exogenous contrast (i.e. iodine) injection and ionizing radiation. Arterial Spin Labeling (ASL)-MRI is an emerging technique that quantitatively measures RBF without any contrast agents or ionizing radiation. We compared renal perfusion (RBF/gram tissue) obtained using CTP and ASL-MRI in the left and right cortex and medulla of the same pigs (n=6), and observed a linear fit of ASL-MRI = 0.24*CTP+0.42 ml/ml/min with correlation r²=0.71.

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