Abstract #4882

Quantitative gated and non-gated rat phase contrast MRI: optimized analysis of blood flow and wall shear stress.

Chen-You Huang¹, Chiun-Wei Huang², Shao-Chieh Chiu², Wu-Chung Shen¹, and Shin-Lei Peng¹

¹Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, ²Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital

Goals of this study are to test effects of gated/non-gated, velocity encoding (VENC) and spatial resolution on blood flow, wall shear stress (WSS) and artery area when performing phase-contrast (PC) MRI for rat common carotid artery (CCA). Results show the usage of gated instrument can provide more reproducible results. VENC has insignificant influences on flow, WSS and artery area. To compromise the trade-off between accuracy and time-consuming, the resolution of 0.21 mm is suggested for extracting hemodynamic information about rat CCA.

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