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Abstract #4906

Ultra-fast balanced SSFP signal enhancement ratio mapping of the human lung parenchyma at 1.5T

Orso Pusterla1,2, Gregor Sommer3, Mark Wiese4, Didier Lardinois4, Michael Tamm5, Jens Bremerich3, Francesco Santini1,2, Grzegorz Bauman1,2, and Oliver Bieri1,2

1Department of Radiology, Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland, 2Department of Biomedical Engineering, University of Basel, Basel, Switzerland, 3Clinic of Radiology and Nuclear Medicine, Cardiac and Thoracic Imaging, University of Basel Hospital, Basel, Switzerland, 4Clinic of Thoracic Surgery, University of Basel Hospital, Basel, Switzerland, 5Clinic of Pneumology, University of Basel Hospital, Basel, Switzerland

In this work, we propose a new conceptual framework for functional pulmonary parenchyma imaging in the clinical setup from two volumetric ultra-fast balanced steady-state free precession (ufSSFP) breath-hold acquisitions before and after contrast agent administration. The resulting signal enhancement ratio (SER) maps of the parenchyma in patients shows similarity to SPECT/CT fusion images. The method requiring only two breath-hold acquisitions is rapid and amenable for clinical use.

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