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Abstract #4926

Effect of Compressed Sensing Reconstruction Parameter on Ultrafast Dynamic Contrast Enhanced Breast MRI

Hajime Sagawa1, Masako Kataoka1, Shotaro Kanao2, Natsuko Onishi2, Maika Urago3, Marcel Dominik Nickel4, Masakazu Toi5, Kyoji Higashimura1, and Kaori Togashi2

1Department of Radiology, Kyoto University Hospital, Kyoto, Japan, 2Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 3Kyoto University Hospital, Kyoto, Japan, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

The aim of this study is to assess the impact of the number of iterations of CS reconstruction on kinetic parameters and the image similarity in DCE-MRI of the breast. Breast examinations include ultrafast DCE-MRI using CS were conducted for 21 patients. The images were reconstructed with different numbers of iterations, and the semi-quantitative and quantitative kinetics parameters were compared. The reconstructed images were evaluated by root mean square error (RMSE) and structural similarity (SSIM) as the quantitative image evaluation. In small number of iteration, the all kinetics parameters were underestimated especially in malignant lesion with hypervascularity.

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