Discrimination between signals from fat and water is of great importance in clinical practice. Chemical saturation, the most widely used fat suppression method, has degraded performance in an in-homogeneity transmit field, and may jeopardize the diagnosis effectiveness. In this abstract, we proposed an improved fat saturation method employing multiple chemical saturation segments. Phantom and volunteer evaluation results show that new method has much less residual lipid signal and can achieve more uniform lipid saturation over big field of view under inhomogeneity condition. Which support the conclusion that proposed method has superior transmit field inhomogeneity immunity.