Abstract #5083

Personalized map to assess diffuse and focal brain damage

Guillaume Bonnier¹, Alexis Roche^2,3, Tom Hilbert^3,4,5, Gunnar Krueger⁶, Cristina Granziera^1,7, and Tobias Kober⁴

¹MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States, ²Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ³Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ⁴Siemens Healthcare AG, Advanced Clinical Imaging Technology, Lausanne, Switzerland, ⁵LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁶Siemens Medical Solutions USA, Inc., Malvern, MA, United States, ⁷Neuroimmunology Unit, Neurology, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland

We propose a new methodology, which is based on the quantification of region-specific brain tissue-properties to provide personalize maps of brain damage in a single patient. To achieve this aim, we used T1, T2, T2* and MTI maps and applied the method to detect brain abnormalities in multiple sclerosis patients.

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