The intervertebral disc without blood supply obtained nutrient substance diffusing from the microcirculation under vertebral endplates. Some studies showed the fat deposition of bone marrow may pressure vessels and blood sinus, which could affect the microcirculation. So the fatty content of bone marrow under vertebral endplates can reflect the degeneration of the vertebral. However, the correlation of fatty content of bone marrow with lumbar intervertebral disc degeneration is not clear. The purpose of our study was to analyze the correlation between bone marrow fatty fraction under vertebral endplates with Pfirrmann Grades and T2* value of lumbar intervertebral disc.