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Abstract #5133

Correlation Between Bone Marrow Fatty Deposition Under Vertebral Endplates with Lumbar Intervertebral Disc Degeneration

Xiaodong Zhang1, Yinxia Zhao1, Yingjie Mei2, and Shaoyong Hu1

1Department of medical radiology, The Third Affiliated Hospital of Southern Medical University(Academy of orthopedics •Guangdong Province), Guangzhou, People's Republic of China, 2Philips Healthcare, Guangzhou, People's Republic of China

The intervertebral disc without blood supply obtained nutrient substance diffusing from the microcirculation under vertebral endplates. Some studies showed the fat deposition of bone marrow may pressure vessels and blood sinus, which could affect the microcirculation. So the fatty content of bone marrow under vertebral endplates can reflect the degeneration of the vertebral. However, the correlation of fatty content of bone marrow with lumbar intervertebral disc degeneration is not clear. The purpose of our study was to analyze the correlation between bone marrow fatty fraction under vertebral endplates with Pfirrmann Grades and T2* value of lumbar intervertebral disc.

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