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Abstract #5185

Classification of White and Brown Adipose Tissue using a Support Vector Machine

Brandon Campbell1,2, Gregory Simchick1,2, Hang Yin3, and Qun Zhao1,2

1Physics and Astronomy, University of Georgia, Athens, GA, United States, 2Bio-Imaging Research Center, University of Georgia, Athens, GA, United States, 3Biochemistry and Molecular Biology, University of Georgia, Athens, GA, United States

Determining the volume and distribution of white adipose tissue (WAT) and brown adipose tissue (BAT) by magnetic resonance imaging (MRI) is clinically important. Previous WAT and BAT classification has relied on using fat fraction and proton relaxation time via fixed multi-peak spectroscopic models. However, the recently proposed Multi-Varying-Peak MR Spectroscopy (MVP-MRS) model allows for the selection of appropriate classification features for differentiation between WAT and BAT. Furthermore, these multi-peak features allow prediction of a ‘browning’ or ‘beigeing’ process of WAT by using a Support Vector Machine (SVM) learning algorithm.

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