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Abstract #5196

Hydration imaging of skeletal muscle tissue based on fat referenced water-fat separated MRI

Thobias Romu1,2, Patrik Tunón3, Fredrik Uhlin 4,5,6, Micael Gylling4, Mårten Segelmark4,6, Anders Fernström4,6, and Olof Dahlqvist Leinhard2,6

1Department of Biomedical Engineering, Linköping University, Linköping, Sweden, 2Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden, 3Advanced MR Analytics AB, Linköping, Sweden, 4Department of Nephrology, Region Östergötland, Sweden, 5Biomedical Engineering, Tallinn University of Technology, Estonia, 6Department of Medical and Health Sciences, Linköping University, Sweden

This work introduces a signal model for imaging of the local hydration of lean tissue, based on water-fat separated MRI. The signal model is calibrated on a healthy cohort and then evaluated on a cohort of hemodialysis patients.

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