Abstract #5196

Hydration imaging of skeletal muscle tissue based on fat referenced water-fat separated MRI

Thobias Romu^1,2, Patrik Tunón³, Fredrik Uhlin ^4,5,6, Micael Gylling⁴, Mårten Segelmark^4,6, Anders Fernström^4,6, and Olof Dahlqvist Leinhard^2,6

¹Department of Biomedical Engineering, Linköping University, Linköping, Sweden, ²Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden, ³Advanced MR Analytics AB, Linköping, Sweden, ⁴Department of Nephrology, Region Östergötland, Sweden, ⁵Biomedical Engineering, Tallinn University of Technology, Estonia, ⁶Department of Medical and Health Sciences, Linköping University, Sweden

This work introduces a signal model for imaging of the local hydration of lean tissue, based on water-fat separated MRI. The signal model is calibrated on a healthy cohort and then evaluated on a cohort of hemodialysis patients.

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