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Abstract #5251

Attentional modulation on the fMRI signal at human visual cortex revealed by fine timing characteristics but not amplitudes

Ying-Hua Chu1, Jo-Fu Lotus Lin1, Pu-Yeh Wu1, Kevin W.-K. Tsai2, Yi-Tien Li1, Yi-Cheng Hsu1, Shang-Yueh Tsai3,4, Wen-Jui Kuo5, and Fa-Hsuan Lin1,6

1Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, 2Aim for the Top University Project Office, National Taiwan Normal University, Taipei, Taiwan, 3Institute of Applied Physics, National Chengchi University, Taipei, Taiwan, 4Research Center for Mind Brain and Learning, National Chengchi University, Taipei, Taiwan, 5Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, 6Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland

By asking subjects engaging a decision task of two levels of difficulty based on foveal stimuli, we measured the BOLD dynamics elicited by checkerboard flashing shown at the peripheral visual fields with two levels of attention using high precision simultaneous-multi-slice inverse imaging (SMS-InI TR = 0.1 s; 5 mm isotropic resolution). Results shown insignificant difference in the amplitude of the BOLD response by two tasks, while time characteristics of onset, time-to-half, and width differ significantly between tasks in the range of hundreds of milliseconds.

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